People

Dr. Sjef Cornelissen

Dr. Sjef Cornelissen
Dr. Sjef Cornelissen
Novozymes A/S
Krogshoejvej 36
2880 Bagsvaerd
Denmark

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Publications
Peer Reviewed Articles
2014
  • Willrodt C., David C., Cornelissen S., Bühler B., Julsing M. K. and Schmid A. (2014)
    Engineering the productivity of recombinant Escherichia coli for limonene formation from glycerol in minimal media.
    Biotechnology Journal, 9(8):1000–1012, DOI-Link
2013
  • Cornelissen S., Julsing M. K., Volmer J., Riechert O., Schmid A. and Bühler B. (2013)
    Whole-cell-based CYP153A6-catalyzed (S)-limonene hydroxylation efficiency depends on host background and profits from monoterpene uptake via AlkL.
    Biotechnology and Bioengineering, 110(5):1282-1292, DOI-Link
2012
  • Cornelissen S., Julsing M. K., Schmid A. and Bühler B. (2012)
    Comparison of microbial hosts and expression systems for mammalian CYP1A1 catalysis.
    Journal of Industrial Microbiology and Biotechnology, 39(2):275-287, DOI-Link
  • Julsing M. K.*, Schrewe M.*, Cornelissen S., Hermann I., Schmid A. and Bühler B. (2012)
    The outer membrane protein AlkL boosts biocatalytic oxyfunctionalization of hydrophobic substrates in E. coli.
    Applied and Environmental Microbiology, 78(16):5724-5733, DOI-Link
    * These authors contributed equally to this work.
2011
  • Cornelissen S., Liu S, Deshmukh A.T., Schmid A. and Bühler B. (2011)
    Cell physiology can determine the efficiency of cytochrome P450-catalyzed C-H-oxyfunctionalization.
    Journal of Industrial Microbiology and Biotechnology, 38:1359-1370, DOI-Link
2009
  • de Souza G. G., Anconi C. P., Cornelissen S., dos Santos H. F., Fortes I. C. and Takahashi J. A. (2009)
    Selective activity of Mucor plumbeus reductase towards (-)-camphorquinone.
    Journal of Industrial Microbiology and Biotechnology, :Epub ahead of print, DOI-Link
2008
  • Julsing M. K., Cornelissen S., Bühler B. and Schmid A. (2008)
    Heme-iron oxygenases: powerful industrial biocatalysts?
    Current Opinion in Chemical Biology, 12(2):177-186, DOI-Link, PubMed
2007
  • Heipieper H. J., Neumann G., Cornelissen S. and Meinhardt F. (2007)
    Solvent-tolerant bacteria for biotransformation in two-phase fermentation systems.
    Applied Microbiology and Biotechnology, 74(5):961-973, DOI-Link, PubMed
2006
  • Lange F., Cornelissen S., Kubac D., Sein M. M., von Sonntag J., Hannich C. B., Golloch A., Heipieper H. J., Möder M. and von Sonntag C. (2006)
    Degradation of macrolide antibiotics by ozone: A mechanistic case study with clarithromycin.
    Chemosphere, 65(1):17 - 23, DOI-Link, PubMed
  • Neumann G., Cornelissen S., van Beukelen F., Hunger S., Lippold H., Loffhagen N., Wick L. Y. and Heipieper H. J. (2006)
    Energetics and surface properties of Pseudomonas putida DOT-T1E in a two-phase fermentation system with 1-decanol as second phase.
    Applied and Environmental Microbiology, 72(6):4232-4238, DOI-Link, PubMed
Books & Bookchapters
2009
  • Heipieper H. J., Cornelissen S. and Pepi M. (2009)
    Surface properties and cellular energetics of bacteria in response to the presence of hydrocarbons.
    in Timmis K. N. Handbook of Hydrocarbon and Lipid Microbiology.
    Springer, Berlin, Germany, Vol. 2, Part 9:1615-1624
Patent applications
2010
  • Pötter M., Schmid A., Bühler B., Hennemann H.-G., Julsing M. K., Schaffer S., Haas T., Schrewe M., Cornelissen S., Roos M. and Häger H. (2010)
    Biocatalytic oxidation process with alkL-gene product.
    WO 2011/131420 / PCT/EP2011/053834 / priority: 10 2010 015 807.0 20.04.2010 DE
Oral Presentations
2009
  • Cornelissen S., Julsing M. K., Bühler B. and Schmid A. (2009)
    A cytochrome P450-based bioprocess for (S)-perillyl alcohol production.
    16th International Conference on Cytochrome P450, Biochemistry, Biophysics, Biotechnology, 21.-25. June 2009, Nago (Okinawa), Japan
2008
  • Cornelissen S., Julsing M. K., Bühler B. and Schmid A. (2008)
    Improved (-)-perillyl alcohol production using CYP153A6 expressed in Pseudomonas putida.
    Biocat 2008, 31st of August - 4th of September 2008, Hamburg, Germany
Posters
2012
  • Julsing M. K., Schrewe M., Cornelissen S., Schmid A. and Bühler B. (2012)
    The outer membrane protein AlkL: a tool for the microbial biotransformation of hydrophobic substrates.
    Gordon Research Conference Biocatalysis, 8. - 13. July 2012, Smithfield, RI, USA
2011
  • Julsing M. K., Schrewe M., Cornelissen S., Schmid A. and Bühler B. (2011)
    Improved biotransformation rates for hydrophobic substrates using ths outer membrane protein AlkL in E. coli.
    Biotrans 2011, 2. - 6. October 2011, Giardini Naxos, Sicily, Italy
  • Lange K., Cornelissen S., Julsing M. K., Bühler B. and Schmid A. (2011)
    Biocatalyst design for the synthesis of cannabinoids in a microbial host: metabolic engineering for the production of monoterpenoids.
    1st European Congress of Applied Biotechnology, September 25-29, 2011, Berlin, Germany
  • Lange K., Cornelissen S., Julsing M. K., Bühler B. and Schmid A. (2011)
    Production of cannabinoids in a microbial host: synthesis of THCA in E. coli.
    CLIB Retreat, April 7, 2011, Bonn, Germany
2010
  • Bühler B., Cornelissen S. and Schmid A. (2010)
    Cell physiology determines the efficiency of cytochrome P450-catalyzed C-H-oxyfunctionalization.
    Gordon Research Conference on Biocatalysis, 11. - 16. July 2010, Smithfield, RI, USA
2009
  • Bühler B., Cornelissen S., Liu S and Schmid A. (2009)
    Whole-cell biocatalysis: An efficient strategy for specific C-H oxyfunctionalizations - P450 catalysis.
    Biotrans 2009, 5th - 9th of July 2009, Bern, Switzerland
  • Cornelissen S., Liu S, Bühler B. and Schmid A. (2009)
    Substrate availability limits CYP153A6-catalyzed (S)-perillyl alcohol production in two-liquid phase biotransformations.
    16th International Conference on Cytochrome P450, Biochemistry, Biophysics, Biotechnology, 21. - 25. June 2009, Nago (Okinawa), Japan
2007
  • Cornelissen S., Julsing M. K., Bühler B. and Schmid A. (2007)
    Evaluation of different recombinant microorganisms expressing mammalian CYP1A1 for productive whole-cell biocatalysis.
    15th International Conference on Cytochromes P450, Biophysics and Functional Genomics, 17. - 21. July 2007, Bled, Slovenia
  • Takahashi J. A., Martins L. R., Souza G. G., Cornelissen S., Silva A. A., Barcellos F. B., de Sousa E. and Abreu L. M. (2007)
    Fungal biotransformations in natural products chemistry.
    The 50th Anniversary Meeting of the Phytochemical Society of Europe, 11. - 14. April 2007, Cambridge, England
2005
  • Kabelitz N., Cornelissen S., Neumann G. and Heipieper H. J. (2005)
    The cis-trans isomerase (cti) of unstaurated fatty acids in the genus Pseudomonas: function and applications.
    10th International Congress on Pseudomonas, 27. - 31. August 2005, Marseille, France
  • Neumann G., Cornelissen S., Hunger S., Zehnsdorf A. and Heipieper H. J. (2005)
    Adaption of Pseudomonas putida DOT-T1E to a second phase of 1-decanol for economically sound two phase biotransformations.
    DECHEMA Technologieforum ‘Weiße Biotechnologie’, 2. - 3. June 2005, Frankfurt am Main, Germany


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